IL-7 is a Key Driver Cytokine in Spondyloarthritis?

The rationale for a type 17 signature in the pathogenesis of spondyloarthritis (SpA) has been increasing and being ratified in studies recently. IL-7 is a cytokine whose ability to stimulate IL-17 production in both innate and adaptive immunity cells has made it a promising target not only for a bet...

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Detalles Bibliográficos
Autores principales: Gonçalves, Rafaela Silva Guimarães, Duarte, Angela Luzia Branco Pinto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6560328/
https://www.ncbi.nlm.nih.gov/pubmed/31276000
http://dx.doi.org/10.1155/2019/7453236
Descripción
Sumario:The rationale for a type 17 signature in the pathogenesis of spondyloarthritis (SpA) has been increasing and being ratified in studies recently. IL-7 is a cytokine whose ability to stimulate IL-17 production in both innate and adaptive immunity cells has made it a promising target not only for a better understanding of the disease as well as an important potential therapeutic target in patients with SpA.

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