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Human host defence peptide LL37 and anti-cyclic citrullinated peptide antibody in early inflammatory arthritis

OBJECTIVE: Antibodies to citrullinated peptides (anti-CCP) develop in individuals predisposed to rheumatoid arthritis (RA). Neutrophil extracellular traps are a major source of citrullinated antigens and the immunomodulatory host defence peptide LL-37. Vitamin D regulates LL-37 expression. This stud...

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Detalles Bibliográficos
Autores principales:	Hitchon, Carol A, Meng, Xiaobo, El Gabalawy, Hani S, Larcombe, Linda
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2019
Materias:	Early Arthritis
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6560668/ https://www.ncbi.nlm.nih.gov/pubmed/31245047 http://dx.doi.org/10.1136/rmdopen-2018-000874

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