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Quality of life reported by survivors after hospitalization for Middle East respiratory syndrome (MERS)

INTRODUCTION: Data are lacking on impact of Middle East Respiratory Syndrome (MERS) on health-related quality of life (HRQoL) among survivors. METHODS: We conducted a cross-sectional survey of MERS survivors who required hospitalization in Saudi Arabia during 2016–2017, approximately 1 year after di...

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Autores principales: Batawi, Sarah, Tarazan, Nehal, Al-Raddadi, Rajaa, Al Qasim, Eman, Sindi, Anees, AL Johni, Sameera, Al-Hameed, Fahad M., Arabi, Yaseen M., Uyeki, Timothy M., Alraddadi, Basem M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6560892/
https://www.ncbi.nlm.nih.gov/pubmed/31186042
http://dx.doi.org/10.1186/s12955-019-1165-2
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author Batawi, Sarah
Tarazan, Nehal
Al-Raddadi, Rajaa
Al Qasim, Eman
Sindi, Anees
AL Johni, Sameera
Al-Hameed, Fahad M.
Arabi, Yaseen M.
Uyeki, Timothy M.
Alraddadi, Basem M.
author_facet Batawi, Sarah
Tarazan, Nehal
Al-Raddadi, Rajaa
Al Qasim, Eman
Sindi, Anees
AL Johni, Sameera
Al-Hameed, Fahad M.
Arabi, Yaseen M.
Uyeki, Timothy M.
Alraddadi, Basem M.
author_sort Batawi, Sarah
collection PubMed
description INTRODUCTION: Data are lacking on impact of Middle East Respiratory Syndrome (MERS) on health-related quality of life (HRQoL) among survivors. METHODS: We conducted a cross-sectional survey of MERS survivors who required hospitalization in Saudi Arabia during 2016–2017, approximately 1 year after diagnosis. The Short-Form General Health Survey 36 (SF-36) was administered by telephone interview to assess 8 quality of life domains for MERS survivors and a sample of survivors of severe acute respiratory infection (SARI) without MERS. We compared mean SF-36 scores of MERS and non-MERS SARI survivors using independent t-test, and compared categorical variables using chi-square test. Adjusted analyses were performed using multiple linear regression. RESULTS: Of 355 MERS survivors, 83 were eligible and 78 agreed to participate. MERS survivors were younger than non-MERS SARI survivors (mean ± SD): (44.9 years ±12.9) vs (50.0 years ±13.6), p = 0.031. Intensive care unit (ICU) admissions were similar for MERS and non-MERS SARI survivors (46.2% vs. 57.1%), p = 0.20. After adjusting for potential confounders, there were no significant differences between MERS and non-MERS SARI survivors in physical component or mental component summary scores. MERS ICU survivors scored lower than MERS survivors not admitted to an ICU for physical function (p = 0.05), general health (p = 0.01), vitality (p = 0.03), emotional role (p = 0.03) and physical component summary (p < 0.02). CONCLUSIONS: Functional scores were similar for MERS and non-MERS SARI survivors. However, MERS survivors of critical illness reported lower quality of life than survivors of less severe illness. Efforts are needed to address the long-term medical and psychological needs of MERS survivors.
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spelling pubmed-65608922019-06-14 Quality of life reported by survivors after hospitalization for Middle East respiratory syndrome (MERS) Batawi, Sarah Tarazan, Nehal Al-Raddadi, Rajaa Al Qasim, Eman Sindi, Anees AL Johni, Sameera Al-Hameed, Fahad M. Arabi, Yaseen M. Uyeki, Timothy M. Alraddadi, Basem M. Health Qual Life Outcomes Research INTRODUCTION: Data are lacking on impact of Middle East Respiratory Syndrome (MERS) on health-related quality of life (HRQoL) among survivors. METHODS: We conducted a cross-sectional survey of MERS survivors who required hospitalization in Saudi Arabia during 2016–2017, approximately 1 year after diagnosis. The Short-Form General Health Survey 36 (SF-36) was administered by telephone interview to assess 8 quality of life domains for MERS survivors and a sample of survivors of severe acute respiratory infection (SARI) without MERS. We compared mean SF-36 scores of MERS and non-MERS SARI survivors using independent t-test, and compared categorical variables using chi-square test. Adjusted analyses were performed using multiple linear regression. RESULTS: Of 355 MERS survivors, 83 were eligible and 78 agreed to participate. MERS survivors were younger than non-MERS SARI survivors (mean ± SD): (44.9 years ±12.9) vs (50.0 years ±13.6), p = 0.031. Intensive care unit (ICU) admissions were similar for MERS and non-MERS SARI survivors (46.2% vs. 57.1%), p = 0.20. After adjusting for potential confounders, there were no significant differences between MERS and non-MERS SARI survivors in physical component or mental component summary scores. MERS ICU survivors scored lower than MERS survivors not admitted to an ICU for physical function (p = 0.05), general health (p = 0.01), vitality (p = 0.03), emotional role (p = 0.03) and physical component summary (p < 0.02). CONCLUSIONS: Functional scores were similar for MERS and non-MERS SARI survivors. However, MERS survivors of critical illness reported lower quality of life than survivors of less severe illness. Efforts are needed to address the long-term medical and psychological needs of MERS survivors. BioMed Central 2019-06-11 /pmc/articles/PMC6560892/ /pubmed/31186042 http://dx.doi.org/10.1186/s12955-019-1165-2 Text en © The Author(s). 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research
Batawi, Sarah
Tarazan, Nehal
Al-Raddadi, Rajaa
Al Qasim, Eman
Sindi, Anees
AL Johni, Sameera
Al-Hameed, Fahad M.
Arabi, Yaseen M.
Uyeki, Timothy M.
Alraddadi, Basem M.
Quality of life reported by survivors after hospitalization for Middle East respiratory syndrome (MERS)
title Quality of life reported by survivors after hospitalization for Middle East respiratory syndrome (MERS)
title_full Quality of life reported by survivors after hospitalization for Middle East respiratory syndrome (MERS)
title_fullStr Quality of life reported by survivors after hospitalization for Middle East respiratory syndrome (MERS)
title_full_unstemmed Quality of life reported by survivors after hospitalization for Middle East respiratory syndrome (MERS)
title_short Quality of life reported by survivors after hospitalization for Middle East respiratory syndrome (MERS)
title_sort quality of life reported by survivors after hospitalization for middle east respiratory syndrome (mers)
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6560892/
https://www.ncbi.nlm.nih.gov/pubmed/31186042
http://dx.doi.org/10.1186/s12955-019-1165-2
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