Discriminant analysis and machine learning approach for evaluating and improving the performance of immunohistochemical algorithms for COO classification of DLBCL

BACKGROUND: Diffuse large B-cell lymphoma (DLBCL) is classified into germinal center-like (GCB) and non-germinal center-like (non-GCB) cell-of-origin groups, entities driven by different oncogenic pathways with different clinical outcomes. DLBCL classification by immunohistochemistry (IHC)-based dec...

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Detalles Bibliográficos
Autores principales: Perfecto-Avalos, Yocanxóchitl, Garcia-Gonzalez, Alejandro, Hernandez-Reynoso, Ana, Sánchez-Ante, Gildardo, Ortiz-Hidalgo, Carlos, Scott, Sean-Patrick, Fuentes-Aguilar, Rita Q., Diaz-Dominguez, Ricardo, León-Martínez, Grettel, Velasco-Vales, Verónica, Cárdenas-Escudero, Mara A., Hernández-Hernández, José A., Santos, Arturo, Borbolla-Escoboza, José R., Villela, Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6560900/
https://www.ncbi.nlm.nih.gov/pubmed/31185999
http://dx.doi.org/10.1186/s12967-019-1951-y

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