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GREACE-assisted adaptive laboratory evolution in endpoint fermentation broth enhances lysine production by Escherichia coli

BACKGROUND: Late-stage fermentation broth contains high concentrations of target chemicals. Additionally, it contains various cellular metabolites which have leaked from lysed cells, which would exert multifactorial stress to industrial hyperproducers and perturb both cellular metabolism and product...

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Detalles Bibliográficos
Autores principales:	Wang, Xiaowei, Li, Qinggang, Sun, Cunmin, Cai, Zhen, Zheng, Xiaomei, Guo, Xuan, Ni, Xiaomeng, Zhou, Wenjuan, Guo, Yanmei, Zheng, Ping, Chen, Ning, Sun, Jibin, Li, Yin, Ma, Yanhe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6560909/ https://www.ncbi.nlm.nih.gov/pubmed/31186003 http://dx.doi.org/10.1186/s12934-019-1153-6

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