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Metformin-associated lactic acidosis treated successfully by peritoneal dialysis in a resource limited setting: case report

Metformin is a commonly used treatment modality in type 2 diabetes mellitus with lactic acidosis as a rare but life-threatening side effect. In this case report we highlight the importance of recognizing this uncommon side effect and the treatment options in a resource limited situation. We present...

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Detalles Bibliográficos
Autores principales: Elmezughi, Khaled, Ekpebegh, Chukwuma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The African Field Epidemiology Network 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6560943/
https://www.ncbi.nlm.nih.gov/pubmed/31223402
http://dx.doi.org/10.11604/pamj.2019.32.112.18271
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author Elmezughi, Khaled
Ekpebegh, Chukwuma
author_facet Elmezughi, Khaled
Ekpebegh, Chukwuma
author_sort Elmezughi, Khaled
collection PubMed
description Metformin is a commonly used treatment modality in type 2 diabetes mellitus with lactic acidosis as a rare but life-threatening side effect. In this case report we highlight the importance of recognizing this uncommon side effect and the treatment options in a resource limited situation. We present a 14-year-old African girl who ingested an unknown amount of metformin intentionally after an argument with her mother. She was referred late to our institution in severe lactic acidosis. Lactic acidosis resolved with appropriate treatment including peritoneal dialysis. We conclude that in resource constrained settings, peritoneal dialysis may be used for metformin associated lactic acidosis with favourable outcome.
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spelling pubmed-65609432019-06-20 Metformin-associated lactic acidosis treated successfully by peritoneal dialysis in a resource limited setting: case report Elmezughi, Khaled Ekpebegh, Chukwuma Pan Afr Med J Case Report Metformin is a commonly used treatment modality in type 2 diabetes mellitus with lactic acidosis as a rare but life-threatening side effect. In this case report we highlight the importance of recognizing this uncommon side effect and the treatment options in a resource limited situation. We present a 14-year-old African girl who ingested an unknown amount of metformin intentionally after an argument with her mother. She was referred late to our institution in severe lactic acidosis. Lactic acidosis resolved with appropriate treatment including peritoneal dialysis. We conclude that in resource constrained settings, peritoneal dialysis may be used for metformin associated lactic acidosis with favourable outcome. The African Field Epidemiology Network 2019-03-11 /pmc/articles/PMC6560943/ /pubmed/31223402 http://dx.doi.org/10.11604/pamj.2019.32.112.18271 Text en © Khaled Elmezughi et al. http://creativecommons.org/licenses/by/2.0/ The Pan African Medical Journal - ISSN 1937-8688. This is an Open Access article distributed under the terms of the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Elmezughi, Khaled
Ekpebegh, Chukwuma
Metformin-associated lactic acidosis treated successfully by peritoneal dialysis in a resource limited setting: case report
title Metformin-associated lactic acidosis treated successfully by peritoneal dialysis in a resource limited setting: case report
title_full Metformin-associated lactic acidosis treated successfully by peritoneal dialysis in a resource limited setting: case report
title_fullStr Metformin-associated lactic acidosis treated successfully by peritoneal dialysis in a resource limited setting: case report
title_full_unstemmed Metformin-associated lactic acidosis treated successfully by peritoneal dialysis in a resource limited setting: case report
title_short Metformin-associated lactic acidosis treated successfully by peritoneal dialysis in a resource limited setting: case report
title_sort metformin-associated lactic acidosis treated successfully by peritoneal dialysis in a resource limited setting: case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6560943/
https://www.ncbi.nlm.nih.gov/pubmed/31223402
http://dx.doi.org/10.11604/pamj.2019.32.112.18271
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