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Metformin-associated lactic acidosis treated successfully by peritoneal dialysis in a resource limited setting: case report
Metformin is a commonly used treatment modality in type 2 diabetes mellitus with lactic acidosis as a rare but life-threatening side effect. In this case report we highlight the importance of recognizing this uncommon side effect and the treatment options in a resource limited situation. We present...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The African Field Epidemiology Network
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6560943/ https://www.ncbi.nlm.nih.gov/pubmed/31223402 http://dx.doi.org/10.11604/pamj.2019.32.112.18271 |
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author | Elmezughi, Khaled Ekpebegh, Chukwuma |
author_facet | Elmezughi, Khaled Ekpebegh, Chukwuma |
author_sort | Elmezughi, Khaled |
collection | PubMed |
description | Metformin is a commonly used treatment modality in type 2 diabetes mellitus with lactic acidosis as a rare but life-threatening side effect. In this case report we highlight the importance of recognizing this uncommon side effect and the treatment options in a resource limited situation. We present a 14-year-old African girl who ingested an unknown amount of metformin intentionally after an argument with her mother. She was referred late to our institution in severe lactic acidosis. Lactic acidosis resolved with appropriate treatment including peritoneal dialysis. We conclude that in resource constrained settings, peritoneal dialysis may be used for metformin associated lactic acidosis with favourable outcome. |
format | Online Article Text |
id | pubmed-6560943 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | The African Field Epidemiology Network |
record_format | MEDLINE/PubMed |
spelling | pubmed-65609432019-06-20 Metformin-associated lactic acidosis treated successfully by peritoneal dialysis in a resource limited setting: case report Elmezughi, Khaled Ekpebegh, Chukwuma Pan Afr Med J Case Report Metformin is a commonly used treatment modality in type 2 diabetes mellitus with lactic acidosis as a rare but life-threatening side effect. In this case report we highlight the importance of recognizing this uncommon side effect and the treatment options in a resource limited situation. We present a 14-year-old African girl who ingested an unknown amount of metformin intentionally after an argument with her mother. She was referred late to our institution in severe lactic acidosis. Lactic acidosis resolved with appropriate treatment including peritoneal dialysis. We conclude that in resource constrained settings, peritoneal dialysis may be used for metformin associated lactic acidosis with favourable outcome. The African Field Epidemiology Network 2019-03-11 /pmc/articles/PMC6560943/ /pubmed/31223402 http://dx.doi.org/10.11604/pamj.2019.32.112.18271 Text en © Khaled Elmezughi et al. http://creativecommons.org/licenses/by/2.0/ The Pan African Medical Journal - ISSN 1937-8688. This is an Open Access article distributed under the terms of the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Elmezughi, Khaled Ekpebegh, Chukwuma Metformin-associated lactic acidosis treated successfully by peritoneal dialysis in a resource limited setting: case report |
title | Metformin-associated lactic acidosis treated successfully by peritoneal dialysis in a resource limited setting: case report |
title_full | Metformin-associated lactic acidosis treated successfully by peritoneal dialysis in a resource limited setting: case report |
title_fullStr | Metformin-associated lactic acidosis treated successfully by peritoneal dialysis in a resource limited setting: case report |
title_full_unstemmed | Metformin-associated lactic acidosis treated successfully by peritoneal dialysis in a resource limited setting: case report |
title_short | Metformin-associated lactic acidosis treated successfully by peritoneal dialysis in a resource limited setting: case report |
title_sort | metformin-associated lactic acidosis treated successfully by peritoneal dialysis in a resource limited setting: case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6560943/ https://www.ncbi.nlm.nih.gov/pubmed/31223402 http://dx.doi.org/10.11604/pamj.2019.32.112.18271 |
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