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Evidence that Ergosterol Biosynthesis Modulates Activity of the Pdr1 Transcription Factor in Candida glabrata

A crucial limitation in antifungal chemotherapy is the limited number of antifungal drugs currently available. Azole drugs represent the most commonly used chemotherapeutic, and loss of efficacy of these drugs is a major risk factor in successful treatment of a variety of fungal diseases. Candida gl...

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Detalles Bibliográficos
Autores principales: Vu, Bao Gia, Thomas, Grace Heredge, Moye-Rowley, W. Scott
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561024/
https://www.ncbi.nlm.nih.gov/pubmed/31186322
http://dx.doi.org/10.1128/mBio.00934-19