Cargando…
Postpartum Sequelae of the Hypertensive Diseases of Pregnancy: A Pilot Study
BACKGROUND: Hypertensive disorders are one of the most common medical conditions that may complicate pregnancy. Postpartum blood pressure (BP) pattern is, however, less clear in affected women and decision to discharge them is usually decided arbitrarily. MATERIALS AND METHODS: A cohort study conduc...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561077/ https://www.ncbi.nlm.nih.gov/pubmed/31198271 http://dx.doi.org/10.4103/nmj.NMJ_101_18 |
_version_ | 1783426086351142912 |
---|---|
author | Babah, Ochuwa Adiketu Olaleye, Olalekan Afolabi, Bosede B. |
author_facet | Babah, Ochuwa Adiketu Olaleye, Olalekan Afolabi, Bosede B. |
author_sort | Babah, Ochuwa Adiketu |
collection | PubMed |
description | BACKGROUND: Hypertensive disorders are one of the most common medical conditions that may complicate pregnancy. Postpartum blood pressure (BP) pattern is, however, less clear in affected women and decision to discharge them is usually decided arbitrarily. MATERIALS AND METHODS: A cohort study conducted at Lagos University Teaching Hospital, Lagos, Nigeria, aimed at determining the proportion of pregnant women with pregnancy-induced hypertension (PIH) and preeclampsia (PE) whose BP remains elevated 6 weeks postdelivery and factors associated with the persistent rise. Fifteen women each with PIH and PE were studied in different phases of pregnancy and followed up until 6 weeks postdelivery. Fifteen normotensive pregnant women served as controls. BP patterns were monitored and fasting lipid levels, serum creatinine, fasting glucose profile (FGP), and FGP/insulin ratio were assayed. Data were analyzed with IBM SPSS version 20. RESULTS: Proportion of women with PIH or PE who had persistent hypertension at 6 weeks postpartum was 3/29 (10.3%), risk ratio of 1.1. No statistically significant association was found between mean arterial BP at 6 weeks postpartum and age, parity, gestational age at delivery, body mass index, and family history of hypertension. Serum creatinine level showed moderate correlation with persistent hypertension at 6 weeks postpartum (r = 0.441,P = 0.006), with sensitivity of 100% and specificity of 81.8% at cutoff value of 1.2 mg/dL in detecting pregnant women with hypertensive disorders who will likely remain hypertensive at 6 weeks postpartum. CONCLUSION: There is a need for long-term follow-up of women with PIH/PE beyond puerperium. |
format | Online Article Text |
id | pubmed-6561077 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-65610772019-06-13 Postpartum Sequelae of the Hypertensive Diseases of Pregnancy: A Pilot Study Babah, Ochuwa Adiketu Olaleye, Olalekan Afolabi, Bosede B. Niger Med J Original Article BACKGROUND: Hypertensive disorders are one of the most common medical conditions that may complicate pregnancy. Postpartum blood pressure (BP) pattern is, however, less clear in affected women and decision to discharge them is usually decided arbitrarily. MATERIALS AND METHODS: A cohort study conducted at Lagos University Teaching Hospital, Lagos, Nigeria, aimed at determining the proportion of pregnant women with pregnancy-induced hypertension (PIH) and preeclampsia (PE) whose BP remains elevated 6 weeks postdelivery and factors associated with the persistent rise. Fifteen women each with PIH and PE were studied in different phases of pregnancy and followed up until 6 weeks postdelivery. Fifteen normotensive pregnant women served as controls. BP patterns were monitored and fasting lipid levels, serum creatinine, fasting glucose profile (FGP), and FGP/insulin ratio were assayed. Data were analyzed with IBM SPSS version 20. RESULTS: Proportion of women with PIH or PE who had persistent hypertension at 6 weeks postpartum was 3/29 (10.3%), risk ratio of 1.1. No statistically significant association was found between mean arterial BP at 6 weeks postpartum and age, parity, gestational age at delivery, body mass index, and family history of hypertension. Serum creatinine level showed moderate correlation with persistent hypertension at 6 weeks postpartum (r = 0.441,P = 0.006), with sensitivity of 100% and specificity of 81.8% at cutoff value of 1.2 mg/dL in detecting pregnant women with hypertensive disorders who will likely remain hypertensive at 6 weeks postpartum. CONCLUSION: There is a need for long-term follow-up of women with PIH/PE beyond puerperium. Wolters Kluwer - Medknow 2018 /pmc/articles/PMC6561077/ /pubmed/31198271 http://dx.doi.org/10.4103/nmj.NMJ_101_18 Text en Copyright: © 2019 Nigerian Medical Journal http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Original Article Babah, Ochuwa Adiketu Olaleye, Olalekan Afolabi, Bosede B. Postpartum Sequelae of the Hypertensive Diseases of Pregnancy: A Pilot Study |
title | Postpartum Sequelae of the Hypertensive Diseases of Pregnancy: A Pilot Study |
title_full | Postpartum Sequelae of the Hypertensive Diseases of Pregnancy: A Pilot Study |
title_fullStr | Postpartum Sequelae of the Hypertensive Diseases of Pregnancy: A Pilot Study |
title_full_unstemmed | Postpartum Sequelae of the Hypertensive Diseases of Pregnancy: A Pilot Study |
title_short | Postpartum Sequelae of the Hypertensive Diseases of Pregnancy: A Pilot Study |
title_sort | postpartum sequelae of the hypertensive diseases of pregnancy: a pilot study |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561077/ https://www.ncbi.nlm.nih.gov/pubmed/31198271 http://dx.doi.org/10.4103/nmj.NMJ_101_18 |
work_keys_str_mv | AT babahochuwaadiketu postpartumsequelaeofthehypertensivediseasesofpregnancyapilotstudy AT olaleyeolalekan postpartumsequelaeofthehypertensivediseasesofpregnancyapilotstudy AT afolabibosedeb postpartumsequelaeofthehypertensivediseasesofpregnancyapilotstudy |