Cargando…
Unsupervised determination of protein crystal structures
We present a method for automatic solution of protein crystal structures. The method proceeds with a single initial model obtained, for instance, by molecular replacement (MR). If a good-quality search model is not available, as often is the case with MR of distant homologs, our method first can aut...
Autores principales: | Ufimtsev, Ivan S., Levitt, Michael |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561213/ https://www.ncbi.nlm.nih.gov/pubmed/31088963 http://dx.doi.org/10.1073/pnas.1821512116 |
Ejemplares similares
-
Solving the structure of Lgl2, a difficult blind test of unsupervised structure determination
por: Ufimtsev, Ivan S., et al.
Publicado: (2019) -
Biological structure and function emerge from scaling unsupervised learning to 250 million protein sequences
por: Rives, Alexander, et al.
Publicado: (2021) -
Unsupervised neural network models of the ventral visual stream
por: Zhuang, Chengxu, et al.
Publicado: (2021) -
High-throughput cryo-ET structural pattern mining by unsupervised deep iterative subtomogram clustering
por: Zeng, Xiangrui, et al.
Publicado: (2023) -
Crystal structure of the FERM-folded talin head reveals the determinants for integrin binding
por: Zhang, Pingfeng, et al.
Publicado: (2020)