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Synthetic Gene Circuits Enable Systems-Level Biosensor Trigger Discovery at the Host-Microbe Interface

Engineering synthetic circuits into intestinal bacteria to sense, record, and respond to in vivo signals is a promising new approach for the diagnosis, treatment, and prevention of disease. However, because the design of disease-responsive circuits is limited by a relatively small pool of known bios...

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Detalles Bibliográficos
Autores principales:	Naydich, Alexander D., Nangle, Shannon N., Bues, Johannes J., Trivedi, Disha, Nissar, Nabeel, Inniss, Mara C., Niederhuber, Matthew J., Way, Jeffrey C., Silver, Pamela A., Riglar, David T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561318/ https://www.ncbi.nlm.nih.gov/pubmed/31186335 http://dx.doi.org/10.1128/mSystems.00125-19

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