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Systems Analyses Reveal the Resilience of Escherichia coli Physiology during Accumulation and Export of the Nonnative Organic Acid Citramalate

Productivity of bacterial cell factories is frequently compromised by stresses imposed by recombinant protein synthesis and carbon-to-product conversion, but little is known about these bioprocesses at a systems level. Production of the unnatural metabolite citramalate in Escherichia coli requires t...

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Detalles Bibliográficos
Autores principales:	Webb, Joseph, Springthorpe, Vicki, Rossoni, Luca, Minde, David-Paul, Langer, Swen, Walker, Heather, Alstrom-Moore, Amias, Larson, Tony, Lilley, Kathryn, Eastham, Graham, Stephens, Gill, Thomas, Gavin H., Kelly, David J., Green, Jeffrey
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561320/ https://www.ncbi.nlm.nih.gov/pubmed/31186337 http://dx.doi.org/10.1128/mSystems.00187-19

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