Alcohol Use Disorder and Traumatic Brain Injury

Alcohol use and traumatic brain injury (TBI) are inextricably and bidirectionally linked. Alcohol intoxication is one of the strongest predictors of TBI, and a substantial proportion of TBIs occur in intoxicated individuals. An inverse relationship is also emerging, such that TBI can serve as a risk...

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Detalles Bibliográficos
Autores principales: Weil, Zachary M., Corrigan, John D., Karelina, Kate
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Institute on Alcohol Abuse and Alcoholism 2018
Materias:
Alcohol Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561403/
https://www.ncbi.nlm.nih.gov/pubmed/31198656
Descripción
Sumario:Alcohol use and traumatic brain injury (TBI) are inextricably and bidirectionally linked. Alcohol intoxication is one of the strongest predictors of TBI, and a substantial proportion of TBIs occur in intoxicated individuals. An inverse relationship is also emerging, such that TBI can serve as a risk factor for, or modulate the course of, alcohol use disorder (AUD). Critically, alcohol use after TBI is a key predictor of rehabilitation outcomes, prognosis, and additional head injuries. This review provides a general overview of the bidirectional relationship between TBI and AUD and a discussion of potential neuropsychological and neurobiological mechanisms that might underlie the relationship.

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