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Targeting miR-155-5p and miR-221-3p by peptide nucleic acids induces caspase-3 activation and apoptosis in temozolomide-resistant T98G glioma cells

The present study investigated the effects of the combined treatment of two peptide nucleic acids (PNAs), directed against microRNAs involved in caspase-3 mRNA regulation (miR-155-5p and miR-221-3p) in the temozolomide (TMZ)-resistant T98G glioma cell line. These PNAs were conjugated with an octaarg...

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Detalles Bibliográficos
Autores principales:	Milani, Roberta, Brognara, Eleonora, Fabbri, Enrica, Manicardi, Alex, Corradini, Roberto, Finotti, Alessia, Gasparello, Jessica, Borgatti, Monica, Cosenza, Lucia Carmela, Lampronti, Ilaria, Dechecchi, Maria Cristina, Cabrini, Giulio, Gambari, Roberto
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2019
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561624/ https://www.ncbi.nlm.nih.gov/pubmed/31180529 http://dx.doi.org/10.3892/ijo.2019.4810

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