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Metformin Delays Satellite Cell Activation and Maintains Quiescence

The regeneration of the muscle tissue relies on the capacity of the satellite stem cell (SC) population to exit quiescence, divide asymmetrically, proliferate, and differentiate. In age-related muscle atrophy (sarcopenia) and several dystrophies, regeneration cannot compensate for the loss of muscle...

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Detalles Bibliográficos
Autores principales: Pavlidou, Theodora, Marinkovic, Milica, Rosina, Marco, Fuoco, Claudia, Vumbaca, Simone, Gargioli, Cesare, Castagnoli, Luisa, Cesareni, Gianni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561664/
https://www.ncbi.nlm.nih.gov/pubmed/31249600
http://dx.doi.org/10.1155/2019/5980465