Cargando…
Metformin Delays Satellite Cell Activation and Maintains Quiescence
The regeneration of the muscle tissue relies on the capacity of the satellite stem cell (SC) population to exit quiescence, divide asymmetrically, proliferate, and differentiate. In age-related muscle atrophy (sarcopenia) and several dystrophies, regeneration cannot compensate for the loss of muscle...
Autores principales: | Pavlidou, Theodora, Marinkovic, Milica, Rosina, Marco, Fuoco, Claudia, Vumbaca, Simone, Gargioli, Cesare, Castagnoli, Luisa, Cesareni, Gianni |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561664/ https://www.ncbi.nlm.nih.gov/pubmed/31249600 http://dx.doi.org/10.1155/2019/5980465 |
Ejemplares similares
-
Regulation of myoblast differentiation by metabolic perturbations induced by metformin
por: Pavlidou, Theodora, et al.
Publicado: (2017) -
Fibro-adipogenic progenitors of dystrophic mice are insensitive to NOTCH regulation of adipogenesis
por: Marinkovic, Milica, et al.
Publicado: (2019) -
SCA-1 micro-heterogeneity in the fate decision of dystrophic fibro/adipogenic progenitors
por: Giuliani, Giulio, et al.
Publicado: (2021) -
Characterization of the Skeletal Muscle Secretome Reveals a Role for Extracellular Vesicles and IL1α/IL1β in Restricting Fibro/Adipogenic Progenitor Adipogenesis
por: Vumbaca, Simone, et al.
Publicado: (2021) -
The immunosuppressant drug azathioprine restrains adipogenesis of muscle Fibro/Adipogenic Progenitors from dystrophic mice by affecting AKT signaling
por: Reggio, Alessio, et al.
Publicado: (2019)