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Auranofin Inhibits RANKL-Induced Osteoclastogenesis by Suppressing Inhibitors of κB Kinase and Inflammasome-Mediated Interleukin-1β Secretion
Osteoporosis is a degenerative metabolic disease caused by an imbalance between osteogenesis and osteoclastogenesis. Increased levels of proinflammatory cytokines combined with decreased estrogen levels, which are commonly seen in postmenopausal women, can lead to overactivation of osteoclasts. Ther...
Autores principales: | Kim, Hyun Young, Kim, Kyeong Seok, Kim, Myung Ji, Kim, Hyung-Shik, Lee, Kwang-Youl, Kang, Keon Wook |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561666/ https://www.ncbi.nlm.nih.gov/pubmed/31275508 http://dx.doi.org/10.1155/2019/3503912 |
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