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Structure of the gene therapy vector, adeno-associated virus with its cell receptor, AAVR

Adeno-associated virus (AAV) vectors are preeminent in emerging clinical gene therapies. Generalizing beyond the most tractable genetic diseases will require modulation of cell specificity and immune neutralization. Interactions of AAV with its cellular receptor, AAVR, are key to understanding cell-...

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Detalles Bibliográficos
Autores principales:	Meyer, Nancy L, Hu, Guiqing, Davulcu, Omar, Xie, Qing, Noble, Alex J, Yoshioka, Craig, Gingerich, Drew S, Trzynka, Andrew, David, Larry, Stagg, Scott M, Chapman, Michael Stewart
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2019
Materias:	Microbiology and Infectious Disease
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561701/ https://www.ncbi.nlm.nih.gov/pubmed/31115336 http://dx.doi.org/10.7554/eLife.44707

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