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A counter gradient of Activin A and follistatin instructs the timing of hair cell differentiation in the murine cochlea

The mammalian auditory sensory epithelium has one of the most stereotyped cellular patterns known in vertebrates. Mechano-sensory hair cells are arranged in precise rows, with one row of inner and three rows of outer hair cells spanning the length of the spiral-shaped sensory epithelium. Aiding such...

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Detalles Bibliográficos
Autores principales: Prajapati-DiNubila, Meenakshi, Benito-Gonzalez, Ana, Golden, Erin Jennifer, Zhang, Shuran, Doetzlhofer, Angelika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561706/
https://www.ncbi.nlm.nih.gov/pubmed/31187730
http://dx.doi.org/10.7554/eLife.47613