Phosphorylation-mediated interactions with TOPBP1 couple 53BP1 and 9-1-1 to control the G1 DNA damage checkpoint

Coordination of the cellular response to DNA damage is organised by multi-domain ‘scaffold’ proteins, including 53BP1 and TOPBP1, which recognise post-translational modifications such as phosphorylation, methylation and ubiquitylation on other proteins, and are themselves carriers of such regulatory...

Descripción completa

Detalles Bibliográficos
Autores principales: Bigot, Nicolas, Day, Matthew, Baldock, Robert A, Watts, Felicity Z, Oliver, Antony W, Pearl, Laurence H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561707/
https://www.ncbi.nlm.nih.gov/pubmed/31135337
http://dx.doi.org/10.7554/eLife.44353

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561707/
https://www.ncbi.nlm.nih.gov/pubmed/31135337
http://dx.doi.org/10.7554/eLife.44353

Ejemplares similares