Functional Landscape of PCGF Proteins Reveals Both RING1A/B-Dependent-and RING1A/B-Independent-Specific Activities

Polycomb repressive complexes 1 and 2 (PRC1 and PRC2) control cell identity by establishing facultative heterochromatin repressive domains at common sets of target genes. PRC1, which deposits H2Aub1 through the E3 ligases RING1A/B, forms six biochemically distinct subcomplexes depending on the assem...

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Detalles Bibliográficos
Autores principales: Scelfo, Andrea, Fernández-Pérez, Daniel, Tamburri, Simone, Zanotti, Marika, Lavarone, Elisa, Soldi, Monica, Bonaldi, Tiziana, Ferrari, Karin Johanna, Pasini, Diego
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561742/
https://www.ncbi.nlm.nih.gov/pubmed/31029542
http://dx.doi.org/10.1016/j.molcel.2019.04.002

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