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Evolution of protein interfaces in multimers and fibrils

A majority of cellular proteins function as part of multimeric complexes of two or more subunits. Multimer formation requires interactions between protein surfaces that lead to closed structures, such as dimers and tetramers. If proteins interact in an open-ended way, uncontrolled growth of fibrils...

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Detalles Bibliográficos
Autores principales: Zabel, W. Jeffrey, Hagner, Kyle P., Livesey, Benjamin J., Marsh, Joseph A., Setayeshgar, Sima, Lynch, Michael, Higgs, Paul G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AIP Publishing LLC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561775/
https://www.ncbi.nlm.nih.gov/pubmed/31202237
http://dx.doi.org/10.1063/1.5086042

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