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FGF1(ΔHBS) ameliorates chronic kidney disease via PI3K/AKT mediated suppression of oxidative stress and inflammation

Currently, there is a lack of effective therapeutic approaches to the treatment of chronic kidney disease (CKD) with irreversible deterioration of renal function. This study aimed to investigate the ability of mutant FGF1 (FGF1(ΔHBS), which has reduced mitogenic activity) to alleviate CKD and to stu...

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Detalles Bibliográficos
Autores principales:	Wang, Dezhong, Jin, Mengyun, Zhao, Xinyu, Zhao, Tianyang, Lin, Wei, He, Zhengle, Fan, Miaojuan, Jin, Wei, Zhou, Jie, Jin, Lingwei, Zheng, Chao, Jin, Hui, Zhao, Yushuo, Li, Xiaokun, Ying, Lei, Wang, Yang, Zhu, Guanghui, Huang, Zhifeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561918/ https://www.ncbi.nlm.nih.gov/pubmed/31189876 http://dx.doi.org/10.1038/s41419-019-1696-9

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