ATR mediates cisplatin resistance in 3D-cultured breast cancer cells via translesion DNA synthesis modulation

Tissue architecture and cell–extracellular matrix (cell–ECM) interaction determine the organ specificity; however, the influences of these factors on anticancer drugs preclinical studies are highly neglected. For considering such aspects, three-dimensional (3D) cell culture models are relevant tools...

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Detalles Bibliográficos
Autores principales: Gomes, Luciana Rodrigues, Rocha, Clarissa Ribeiro Reily, Martins, Davi Jardim, Fiore, Ana Paula Zen Petisco, Kinker, Gabriela Sarti, Bruni-Cardoso, Alexandre, Menck, Carlos Frederico Martins
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561919/
https://www.ncbi.nlm.nih.gov/pubmed/31189884
http://dx.doi.org/10.1038/s41419-019-1689-8

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