Ets-1 deficiency alleviates nonalcoholic steatohepatitis via weakening TGF-β1 signaling-mediated hepatocyte apoptosis

Hepatocyte apoptosis is a hallmark of nonalcoholic steatohepatitis (NASH) and contributes to liver injury, fibrosis, and inflammation. However, the molecular mechanisms underlying excessive hepatocyte apoptosis in NASH remain largely unknown. This study aimed to explore whether and how the v-ets avi...

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Detalles Bibliográficos
Autores principales: Liu, Dechen, Wang, Kai, Li, Kai, Xu, Rufeng, Chang, Xiaoai, Zhu, Yunxia, Sun, Peng, Han, Xiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561928/
https://www.ncbi.nlm.nih.gov/pubmed/31189885
http://dx.doi.org/10.1038/s41419-019-1672-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561928/
https://www.ncbi.nlm.nih.gov/pubmed/31189885
http://dx.doi.org/10.1038/s41419-019-1672-4

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