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Activation of PTEN by inhibition of TRPV4 suppresses colon cancer development

Transient receptor potential vanilloid type 4 (TRPV4) is a Ca(2+)-permeable cation channel that is known to be an osmosensor and thermosensor. Currently, limited evidence shows that TRPV4 plays opposite roles in either promoting or inhibiting cancer development in different cancer types. Furthermore...

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Detalles Bibliográficos
Autores principales: Liu, Xiaoyu, Zhang, Peng, Xie, Chuanming, Sham, Kathy W. Y., Ng, Simon S. M., Chen, Yangchao, Cheng, Christopher H. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561944/
https://www.ncbi.nlm.nih.gov/pubmed/31189890
http://dx.doi.org/10.1038/s41419-019-1700-4