Circulating tumor DNA analyses predict progressive disease and indicate trastuzumab-resistant mechanism in advanced gastric cancer

BACKGROUND: Circulating tumor DNA (ctDNA) isolated from plasma contains genetic mutations that can be representative of those found in primary tumor tissue DNA. These samples can provide insights into tumoral heterogeneity in patients with advanced gastric cancer (AGC). Although trastuzumab has been...

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Detalles Bibliográficos
Autores principales: Wang, Yan, Zhao, Chuanhua, Chang, Lianpeng, Jia, Ru, Liu, Rongrui, Zhang, Yun, Gao, Xuan, Li, Jin, Chen, Rongrong, Xia, Xuefeng, Bulbul, Ajaz, Husain, Hatim, Guan, Yanfang, Yi, Xin, Xu, Jianming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Research paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562020/
https://www.ncbi.nlm.nih.gov/pubmed/31031019
http://dx.doi.org/10.1016/j.ebiom.2019.04.003

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