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α‐synuclein RT‐QuIC in cerebrospinal fluid of LRRK2‐linked Parkinson's disease

BACKGROUND: Leucine‐rich kinase 2 (LRRK2)‐linked Parkinson's disease (PD) is clinically indistinguishable from idiopathic PD (IPD). A pleiotropic neuropathology has been recognized but the majority of studies in LRRK2 p.G2019S patients reveal Lewy‐type synucleinopathy as its principal histologi...

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Detalles Bibliográficos
Autores principales: Garrido, Alicia, Fairfoul, Graham, Tolosa, Eduardo S., Martí, Maria José, Green, Alison
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562027/
https://www.ncbi.nlm.nih.gov/pubmed/31211166
http://dx.doi.org/10.1002/acn3.772

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