miRNA contributions to pediatric‐onset multiple sclerosis inferred from GWAS

OBJECTIVE: Onset of multiple sclerosis (MS) occurs in childhood for approximately 5% of cases (pediatric MS, or ped‐MS). Epigenetic influences are strongly implicated in MS pathogenesis in adults, including the contribution from microRNAs (miRNAs), small noncoding RNAs that affect gene expression by...

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Detalles Bibliográficos
Autores principales: Rhead, Brooke, Shao, Xiaorong, Graves, Jennifer S., Chitnis, Tanuja, Waldman, Amy T., Lotze, Timothy, Schreiner, Teri, Belman, Anita, Krupp, Lauren, Greenberg, Benjamin M., Weinstock–Guttman, Bianca, Aaen, Gregory, Tillema, Jan M., Rodriguez, Moses, Hart, Janace, Caillier, Stacy, Ness, Jayne, Harris, Yolanda, Rubin, Jennifer, Candee, Meghan S., Gorman, Mark, Benson, Leslie, Mar, Soe, Kahn, Ilana, Rose, John, Casper, T. Charles, Quach, Hong, Quach, Diana, Schaefer, Catherine, Waubant, Emmanuelle, Barcellos, Lisa F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562070/
https://www.ncbi.nlm.nih.gov/pubmed/31211169
http://dx.doi.org/10.1002/acn3.786

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