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Oncogenic RAC1 and NRAS drive resistance to endoplasmic reticulum stress through MEK/ERK signalling

Cancer cells are able to survive under conditions that cause endoplasmic reticulum stress (ER-stress), and can adapt to this stress by upregulating cell-survival signalling pathways and down-regulating apoptotic pathways. The cellular response to ER-stress is controlled by the unfolded protein respo...

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Detalles Bibliográficos
Autores principales:	Bright, Michael D., Clarke, Paul A., Workman, Paul, Davies, Faith E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Science Ltd 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562199/ https://www.ncbi.nlm.nih.gov/pubmed/29329780 http://dx.doi.org/10.1016/j.cellsig.2018.01.004

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