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Role of Integrins in Resistance to Therapies Targeting Growth Factor Receptors in Cancer

Integrins contribute to cancer progression and aggressiveness by activating intracellular signal transduction pathways and transducing mechanical tension forces. Remarkably, these adhesion receptors share common signaling networks with receptor tyrosine kinases (RTKs) and support their oncogenic act...

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Detalles Bibliográficos
Autores principales:	Cruz da Silva, Elisabete, Dontenwill, Monique, Choulier, Laurence, Lehmann, Maxime
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562376/ https://www.ncbi.nlm.nih.gov/pubmed/31109009 http://dx.doi.org/10.3390/cancers11050692

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