Antitumor Activity of DFX117 by Dual Inhibition of c-Met and PI3Kα in Non-Small Cell Lung Cancer

Aberrant activation of hepatocyte growth factor (HGF)/c-Met signaling pathway caused by gene amplification or mutation plays an important role in tumorigenesis. Therefore, c-Met is considered as an attractive target for cancer therapy and c-Met inhibitors have been developed with great interests. Ho...

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Detalles Bibliográficos
Autores principales: Fan, Yanhua, Ding, Huaiwei, Kim, Donghwa, Bach, Duc-Hiep, Hong, Ji-Young, Xu, Yongnan, Lee, Sang Kook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562471/
https://www.ncbi.nlm.nih.gov/pubmed/31060329
http://dx.doi.org/10.3390/cancers11050627

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562471/
https://www.ncbi.nlm.nih.gov/pubmed/31060329
http://dx.doi.org/10.3390/cancers11050627

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