Single Cell RNA Sequencing Identifies Subsets of Hepatic Stellate Cells and Myofibroblasts in Liver Fibrosis

Activation of hepatic stellate cells (HSCs) and their trans-differentiation towards collagen-secreting myofibroblasts (MFB) promote liver fibrosis progression. During chronic liver disease, resting HSCs become activated by inflammatory and injury signals. However, HSCs/MFB not only produce collagen,...

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Detalles Bibliográficos
Autores principales: Krenkel, Oliver, Hundertmark, Jana, Ritz, Thomas P., Weiskirchen, Ralf, Tacke, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562512/
https://www.ncbi.nlm.nih.gov/pubmed/31137713
http://dx.doi.org/10.3390/cells8050503

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562512/
https://www.ncbi.nlm.nih.gov/pubmed/31137713
http://dx.doi.org/10.3390/cells8050503

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