Targeting Adenosine in Cancer Immunotherapy to Enhance T-Cell Function

T cells play a critical role in cancer control, but a range of potent immunosuppressive mechanisms can be upregulated in the tumor microenvironment (TME) to abrogate their activity. While various immunotherapies (IMTs) aiming at re-invigorating the T-cell-mediated anti-tumor response, such as immune...

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Detalles Bibliográficos
Autores principales: Vigano, Selena, Alatzoglou, Dimitrios, Irving, Melita, Ménétrier-Caux, Christine, Caux, Christophe, Romero, Pedro, Coukos, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562565/
https://www.ncbi.nlm.nih.gov/pubmed/31244820
http://dx.doi.org/10.3389/fimmu.2019.00925

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562565/
https://www.ncbi.nlm.nih.gov/pubmed/31244820
http://dx.doi.org/10.3389/fimmu.2019.00925

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