Cargando…

Oceans as a Source of Immunotherapy

Marine flora is taxonomically diverse, biologically active, and chemically unique. It is an excellent resource, which offers great opportunities for the discovery of new biopharmaceuticals such as immunomodulators and drugs targeting cancerous, inflammatory, microbial, and fungal diseases. The abili...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ahmad, Bilal, Shah, Masaud, Choi, Sangdun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562586/ https://www.ncbi.nlm.nih.gov/pubmed/31083446 http://dx.doi.org/10.3390/md17050282

Ejemplares similares

Mutations in the SARS-CoV-2 spike RBD are responsible for stronger ACE2 binding and poor anti-SARS-CoV mAbs cross-neutralization
por: Shah, Masaud, et al.
Publicado: (2020)

Toll-like Receptor-Dependent Negative Effects of Opioids: A Battle between Analgesia and Hyperalgesia
por: Shah, Masaud, et al.
Publicado: (2017)

Middle East respiratory syndrome coronavirus: transmission, virology and therapeutic targeting to aid in outbreak control
por: Durai, Prasannavenkatesh, et al.
Publicado: (2015)

Recent clinical trends in Toll‐like receptor targeting therapeutics
por: Anwar, Muhammad Ayaz, et al.
Publicado: (2018)

Insights into the species-specific TLR4 signaling mechanism in response to Rhodobacter sphaeroides lipid A detection
por: Anwar, Muhammad Ayaz, et al.
Publicado: (2015)

A structural insight into the negative effects of opioids in analgesia by modulating the TLR4 signaling: An in silico approach
por: Shah, Masaud, et al.
Publicado: (2016)

Structural insights into the Middle East respiratory syndrome coronavirus 4a protein and its dsRNA binding mechanism
por: Batool, Maria, et al.
Publicado: (2017)

A Structure-Based Drug Discovery Paradigm
por: Batool, Maria, et al.
Publicado: (2019)

In silico mechanistic analysis of IRF3 inactivation and high-risk HPV E6 species-dependent drug response
por: Shah, Masaud, et al.
Publicado: (2015)

Structural Mechanism behind Distinct Efficiency of Oct4/Sox2 Proteins in Differentially Spaced DNA Complexes
por: Yesudhas, Dhanusha, et al.
Publicado: (2016)

Unraveling the Tomaralimab Epitope on the Toll-like Receptor 2 via Molecular Dynamics and Deep Learning
por: Ahmad, Bilal, et al.
Publicado: (2022)

EPHB6 mutation induces cell adhesion-mediated paclitaxel resistance via EPHA2 and CDH11 expression
por: Yoon, Sarah, et al.
Publicado: (2019)

Adenylate kinase potentiates the capsular polysaccharide by modulating Cps2D in Streptococcus pneumoniae D39
por: Ghosh, Prachetash, et al.
Publicado: (2018)

Pneumococcal VncR Strain-Specifically Regulates Capsule Polysaccharide Synthesis
por: Ghosh, Prachetash, et al.
Publicado: (2019)

Accelerated NLRP3 inflammasome-inhibitory peptide design using a recurrent neural network model and molecular dynamics simulations
por: Ahmad, Bilal, et al.
Publicado: (2023)

Toll-Like Receptors as a Therapeutic Target in the Era of Immunotherapies
por: Farooq, Mariya, et al.
Publicado: (2021)

Computational-Driven Epitope Verification and Affinity Maturation of TLR4-Targeting Antibodies
por: Ahmad, Bilal, et al.
Publicado: (2021)

Modeling structure–activity relationships with machine learning to identify GSK3-targeted small molecules as potential COVID-19 therapeutics
por: Pirzada, Rameez Hassan, et al.
Publicado: (2023)

Microbial Sources of Exocellular DNA in the Ocean
por: Linney, Morgan D., et al.
Publicado: (2022)

Examination of the ocean as a source for atmospheric microplastics
por: Allen, Steve, et al.
Publicado: (2020)

New cell sources for CAR-based immunotherapy
por: Mazinani, Marzieh, et al.
Publicado: (2023)

Exploring the Binding Mechanism of PF-07321332 SARS-CoV-2 Protease Inhibitor through Molecular Dynamics and Binding Free Energy Simulations
por: Ahmad, Bilal, et al.
Publicado: (2021)

Therapeutic Targeting of Innate Immune Receptors Against SARS-CoV-2 Infection
por: Farooq, Mariya, et al.
Publicado: (2022)

Nanoinformatics: Emerging Databases and Available Tools
por: Panneerselvam, Suresh, et al.
Publicado: (2014)

Acetylation- and Methylation-Related Epigenetic Proteins in the Context of Their Targets
por: Javaid, Nasir, et al.
Publicado: (2017)

Toll-like Receptors from the Perspective of Cancer Treatment
por: Javaid, Nasir, et al.
Publicado: (2020)

Aerosols as a source of dissolved black carbon to the ocean
por: Bao, Hongyan, et al.
Publicado: (2017)

mRNA in cancer immunotherapy: beyond a source of antigen
por: Van Hoecke, Lien, et al.
Publicado: (2021)

Gram-Negative Marine Bacteria: Structural Features of Lipopolysaccharides and Their Relevance for Economically Important Diseases
por: Anwar, Muhammad Ayaz, et al.
Publicado: (2014)

Recent Progress in the Molecular Recognition and Therapeutic Importance of Interleukin-1 Receptor-Associated Kinase 4
por: Patra, Mahesh Chandra, et al.
Publicado: (2016)

Ice sheets as a missing source of silica to the polar oceans
por: Hawkings, Jon R., et al.
Publicado: (2017)

Toll-Like Receptors and Relevant Emerging Therapeutics with Reference to Delivery Methods
por: Javaid, Nasir, et al.
Publicado: (2019)

Structure and Effects of Cyanobacterial Lipopolysaccharides
por: Durai, Prasannavenkatesh, et al.
Publicado: (2015)

TCR-NK Cells: A Novel Source for Adoptive Immunotherapy of Cancer
por: Karahan, Zeynep Sena, et al.
Publicado: (2023)

Omicron: A Heavily Mutated SARS-CoV-2 Variant Exhibits Stronger Binding to ACE2 and Potently Escapes Approved COVID-19 Therapeutic Antibodies
por: Shah, Masaud, et al.
Publicado: (2022)

Sources and Levels of Ambient Ocean Sound near the Antarctic Peninsula
por: Dziak, Robert P., et al.
Publicado: (2015)

The Irony of Iron – Biogenic Iron Oxides as an Iron Source to the Ocean
por: Emerson, David
Publicado: (2016)

Screening and design of anti-diabetic compounds sourced from the leaves of neem (Azadirachta indica)
por: Jalil, Asma, et al.
Publicado: (2013)

Molecular Perspectives of SARS-CoV-2: Pathology, Immune Evasion, and Therapeutic Interventions
por: Shah, Masaud, et al.
Publicado: (2021)

The paradigm of immune escape by SARS-CoV-2 variants and strategies for repositioning subverted mAbs against escaped VOCs
por: Shah, Masaud, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_g5a2bjkhm0f40kota175tbgc9k