TNF-α Modulates P-Glycoprotein Expression and Contributes to Cellular Proliferation via Extracellular Vesicles

P-glycoprotein (Pgp/ABCB1) overexpression is associated with multidrug resistance (MDR) phenotype and, consequently, failure in cancer chemotherapy. However, molecules involved in cell death deregulation may also support MDR. Tumor necrosis factor-alpha (TNF-α) is an important cytokine that may trig...

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Detalles Bibliográficos
Autores principales: S. Berguetti, Tandressa, S. P. Quintaes, Lucas, Hancio Pereira, Thais, Robaina, Marcela C., Cruz, André L. S., C. Maia, Raquel, de Souza, Paloma Silva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562596/
https://www.ncbi.nlm.nih.gov/pubmed/31137684
http://dx.doi.org/10.3390/cells8050500

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