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ZAP-70 Regulates Autoimmune Arthritis via Alterations in T Cell Activation and Apoptosis
T cells play an essential role in the pathogenesis of both human rheumatoid arthritis (RA) and its murine models. A key molecule in T cell activation is ZAP-70, therefore we aimed to investigate the effects of partial ZAP-70 deficiency on the pathogenesis of recombinant human G1(rhG1)-induced arthri...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562615/ https://www.ncbi.nlm.nih.gov/pubmed/31137740 http://dx.doi.org/10.3390/cells8050504 |