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High sensitivity methods to quantify chloroquine and its metabolite in human blood samples using LC–MS/MS

AIM: Chloroquine is an antimalarial drug used in the treatment of Plasmodium vivax malaria. Three methods to quantify chloroquine and its metabolite in blood matrices were developed and validated. METHODOLOGY & RESULTS: Different high-throughput extraction techniques were used to recover the dru...

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Detalles Bibliográficos
Autores principales:	Kaewkhao, Karnrawee, Chotivanich, Kesinee, Winterberg, Markus, Day, Nicholas PJ, Tarning, Joel, Blessborn, Daniel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Future Science Ltd 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562699/ https://www.ncbi.nlm.nih.gov/pubmed/30873854 http://dx.doi.org/10.4155/bio-2018-0202

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