A Transgenic Mouse Model of Pacak–Zhuang Syndrome with An Epas1 Gain-of-Function Mutation

We previously identified a novel syndrome in patients characterized by paraganglioma, somatostatinoma, and polycythemia. In these patients, polycythemia occurs long before any tumor develops, and tumor removal only partially corrects polycythemia, with recurrence occurring shortly after surgery. Gen...

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Detalles Bibliográficos
Autores principales: Wang, Herui, Cui, Jing, Yang, Chunzhang, Rosenblum, Jared S., Zhang, Qi, Song, Qi, Pang, Ying, Fang, Francia, Sun, Mitchell, Dmitriev, Pauline, Gilbert, Mark R., Eisenhofer, Graeme, Pacak, Karel, Zhuang, Zhengping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562734/
https://www.ncbi.nlm.nih.gov/pubmed/31091718
http://dx.doi.org/10.3390/cancers11050667

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