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rEXPAR: An Isothermal Amplification Scheme That Is Robust to Autocatalytic Parasites
[Image: see text] In the absence of DNA, a solution containing the four deoxynucleotidetriphosphates (dNTPs), a DNA polymerase, and a nicking enzyme generates a self-replicating mixture of DNA species called parasite. Parasites are problematic in template-based isothermal amplification schemes such...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American
Chemical Society
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562758/ https://www.ncbi.nlm.nih.gov/pubmed/31074259 http://dx.doi.org/10.1021/acs.biochem.9b00063 |