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ER-Targeted Beclin 1 Supports Autophagosome Biogenesis in the Absence of ULK1 and ULK2 Kinases
Autophagy transports cytoplasmic material and organelles to lysosomes for degradation and recycling. Beclin 1 forms a complex with several other autophagy proteins and functions in the initiation phase of autophagy, but the exact role of Beclin 1 subcellular localization in autophagy initiation is s...
Autores principales: | Anwar, Tahira, Liu, Xiaonan, Suntio, Taina, Marjamäki, Annika, Biazik, Joanna, Chan, Edmond Y. W., Varjosalo, Markku, Eskelinen, Eeva-Liisa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562811/ https://www.ncbi.nlm.nih.gov/pubmed/31108943 http://dx.doi.org/10.3390/cells8050475 |
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