TCam-2 Cells Deficient for SOX2 and FOXA2 Are Blocked in Differentiation and Maintain a Seminoma-Like Cell Fate In Vivo

Testicular germ cell tumors (GCTs) are very common in young men and can be stratified into seminomas and non-seminomas. While seminomas share a similar gene expression and epigenetic profile with primordial germ cells, the stem cell population of the non-seminomas, the embryonal carcinoma (EC), rese...

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Detalles Bibliográficos
Autores principales: Nettersheim, Daniel, Vadder, Saskia, Jostes, Sina, Heimsoeth, Alena, Schorle, Hubert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562827/
https://www.ncbi.nlm.nih.gov/pubmed/31130628
http://dx.doi.org/10.3390/cancers11050728

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562827/
https://www.ncbi.nlm.nih.gov/pubmed/31130628
http://dx.doi.org/10.3390/cancers11050728

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