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TCam-2 Cells Deficient for SOX2 and FOXA2 Are Blocked in Differentiation and Maintain a Seminoma-Like Cell Fate In Vivo

Testicular germ cell tumors (GCTs) are very common in young men and can be stratified into seminomas and non-seminomas. While seminomas share a similar gene expression and epigenetic profile with primordial germ cells, the stem cell population of the non-seminomas, the embryonal carcinoma (EC), rese...

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Detalles Bibliográficos
Autores principales:	Nettersheim, Daniel, Vadder, Saskia, Jostes, Sina, Heimsoeth, Alena, Schorle, Hubert
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562827/ https://www.ncbi.nlm.nih.gov/pubmed/31130628 http://dx.doi.org/10.3390/cancers11050728

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