Cargando…

Oncogenic Signaling in Tumorigenesis and Applications of siRNA Nanotherapeutics in Breast Cancer

Overexpression of oncogenes and cross-talks of the oncoproteins-regulated signaling cascades with other intracellular pathways in breast cancer could lead to massive abnormal signaling with the consequence of tumorigenesis. The ability to identify the genes having vital roles in cancer development w...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kamaruzman, Nur Izyani, Aziz, Noraini Abd, Poh, Chit Laa, Chowdhury, Ezharul Hoque
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562835/ https://www.ncbi.nlm.nih.gov/pubmed/31064156 http://dx.doi.org/10.3390/cancers11050632

Ejemplares similares

Development of MicroRNAs as Potential Therapeutics against Cancer
por: Abd-Aziz, Noraini, et al.
Publicado: (2020)

Carbonate apatite nanoparticles carry siRNA(s) targeting growth factor receptor genes egfr1 and erbb2 to regress mouse breast tumor
por: Tiash, Snigdha, et al.
Publicado: (2017)

siRNAs Targeting Growth Factor Receptor and Anti-Apoptotic Genes Synergistically Kill Breast Cancer Cells through Inhibition of MAPK and PI-3 Kinase Pathways
por: Kamaruzman, Nur Izyani, et al.
Publicado: (2018)

Targeting Cell Adhesion Molecules via Carbonate Apatite-Mediated Delivery of Specific siRNAs to Breast Cancer Cells In Vitro and In Vivo
por: Ashaie, Maeirah Afzal, et al.
Publicado: (2019)

Development of Peptide-Based Vaccines for Cancer
por: Abd-Aziz, Noraini, et al.
Publicado: (2022)

Peptide-siRNA nanotherapeutics in arthritis
por: Pham, Christine T.N., et al.
Publicado: (2015)

The emerging potential of siRNA nanotherapeutics in treatment of arthritis
por: Kumari, Anjali, et al.
Publicado: (2023)

PEGylated Strontium Sulfite Nanoparticles with Spontaneously Formed Surface-Embedded Protein Corona Restrict Off-Target Distribution and Accelerate Breast Tumour-Selective Delivery of siRNA
por: Karim, Md. Emranul, et al.
Publicado: (2022)

Intracellular Delivery of siRNAs Targeting AKT and ERBB2 Genes Enhances Chemosensitization of Breast Cancer Cells in a Culture and Animal Model
por: Fatemian, Tahereh, et al.
Publicado: (2019)

Role of microRNAs in antiviral responses to dengue infection
por: Wong, Rui Rui, et al.
Publicado: (2020)

Engineered Oncolytic Adenoviruses: An Emerging Approach for Cancer Therapy
por: Tan, Ee Wern, et al.
Publicado: (2022)

miRNA: A Promising Therapeutic Target in Cancer
por: Menon, Amrutha, et al.
Publicado: (2022)

Clinical Advances of siRNA-Based Nanotherapeutics for Cancer Treatment
por: Hattab, Dima, et al.
Publicado: (2021)

Reversing multidrug resistance in breast cancer cells by silencing ABC transporter genes with nanoparticle-facilitated delivery of target siRNAs
por: Li, Yong Tsuey, et al.
Publicado: (2012)

Therapeutic Potency of Nanoformulations of siRNAs and shRNAs in Animal Models of Cancers
por: Karim, Md. Emranul, et al.
Publicado: (2018)

Carbonate Apatite and Hydroxyapatite Formulated with Minimal Ingredients to Deliver SiRNA into Breast Cancer Cells In Vitro and In Vivo
por: Islam, Rowshan Ara, et al.
Publicado: (2020)

Carbonate Apatite Nanoparticles-Facilitated Intracellular Delivery of siRNA(s) Targeting Calcium Ion Channels Efficiently Kills Breast Cancer Cells
por: Uddin, Mohammad Borhan, et al.
Publicado: (2018)

Strontium Sulfite: A New pH-Responsive Inorganic Nanocarrier to Deliver Therapeutic siRNAs to Cancer Cells
por: Karim, Md. Emranul, et al.
Publicado: (2019)

A database of breast oncogenic specific siRNAs
por: Tyagi, Atul, et al.
Publicado: (2017)

siRNA‐based nanotherapeutics as emerging modalities for immune‐mediated diseases: A preliminary review
por: Sargazi, Saman, et al.
Publicado: (2022)

Nanotherapeutics Using an HIV-1 Poly A and Transactivator of the HIV-1 LTR-(TAR-) Specific siRNA
por: Mahajan, Supriya D., et al.
Publicado: (2011)

Cytotoxicity Enhancement in Breast Cancer Cells with Carbonate Apatite-Facilitated Intracellular Delivery of Anti-Cancer Drugs
por: Fatemian, Tahereh, et al.
Publicado: (2018)

Retarding breast tumor growth with nanoparticle-facilitated intravenous delivery of BRCA1 and BRCA2 tumor suppressor genes
por: Ibnat, Nabilah, et al.
Publicado: (2023)

Surface-Modification of Carbonate Apatite Nanoparticles Enhances Delivery and Cytotoxicity of Gemcitabine and Anastrozole in Breast Cancer Cells
por: Mozar, Fitya Syarifa, et al.
Publicado: (2017)

Citrate- and Succinate-Modified Carbonate Apatite Nanoparticles with Loaded Doxorubicin Exhibit Potent Anticancer Activity against Breast Cancer Cells
por: Mehbuba Hossain, Sultana, et al.
Publicado: (2018)

The Conserved Molecular Determinants of Virulence in Dengue Virus
por: Ahmad, Zuleeza, et al.
Publicado: (2019)

Correction: Lalani, S. and Poh, C.L. Flavonoids as Antiviral Agents for Enterovirus A71 (EV-A71). Viruses 2020, 12, 184
por: Lalani, Salima, et al.
Publicado: (2020)

Flavonoids as Antiviral Agents for Enterovirus A71 (EV-A71)
por: Lalani, Salima, et al.
Publicado: (2020)

The development of DNA vaccines against SARS-CoV-2
por: Khalid, Kanwal, et al.
Publicado: (2023)

The Promising Potential of Reverse Vaccinology-Based Next-Generation Vaccine Development over Conventional Vaccines against Antibiotic-Resistant Bacteria
por: Khalid, Kanwal, et al.
Publicado: (2023)

Nanoparticles Targeting Receptors on Breast Cancer for Efficient Delivery of Chemotherapeutics
por: Jahan, Sulltana, et al.
Publicado: (2021)

Bioactive nanotherapeutic trends to combat triple negative breast cancer
por: Chowdhury, Pallabita, et al.
Publicado: (2021)

Changes in the EV-A71 Genome through Recombination and Spontaneous Mutations: Impact on Virulence
por: Mandary, Madiiha Bibi, et al.
Publicado: (2018)

Advances in Antigenic Peptide-Based Vaccine and Neutralizing Antibodies against Viruses Causing Hand, Foot, and Mouth Disease
por: Anasir, Mohd Ishtiaq, et al.
Publicado: (2019)

Structural Vaccinology for Viral Vaccine Design
por: Anasir, Mohd Ishtiaq, et al.
Publicado: (2019)

Recent advances in delivery of veterinary DNA vaccines against avian pathogens
por: Jazayeri, Seyed Davoud, et al.
Publicado: (2019)

Development of Universal Influenza Vaccines Targeting Conserved Viral Proteins
por: Jazayeri, Seyed Davoud, et al.
Publicado: (2019)

Insights into innate and adaptive immune responses in vaccine development against EV-A71
por: Lim, Hui Xuan, et al.
Publicado: (2019)

Lentivirus-mediated siRNA knockdown of SPHK1 inhibits proliferation and tumorigenesis of neuroblastoma
por: Su, Lin, et al.
Publicado: (2018)

Peptides as Therapeutic Agents for Dengue Virus
por: Chew, Miaw-Fang, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_otu19utudmfmkgm0vetl3d8o5o