Cargando…
Renieramycin T Induces Lung Cancer Cell Apoptosis by Targeting Mcl-1 Degradation: A New Insight in the Mechanism of Action
Among malignancies, lung cancer is the major cause of cancer death. Despite the advance in lung cancer therapy, the five-year survival rate is extremely restricted due to therapeutic failure and disease relapse. Targeted therapies selectively inhibiting certain molecules in cancer cells have been ac...
Autores principales: | Petsri, Korrakod, Chamni, Supakarn, Suwanborirux, Khanit, Saito, Naoki, Chanvorachote, Pithi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562878/ https://www.ncbi.nlm.nih.gov/pubmed/31117253 http://dx.doi.org/10.3390/md17050301 |
Ejemplares similares
-
5-O-Acetyl-Renieramycin T from Blue Sponge Xestospongia sp. Induces Lung Cancer Stem Cell Apoptosis
por: Chantarawong, Wipa, et al.
Publicado: (2019) -
Light-Mediated Transformation of Renieramycins and Semisynthesis of 4′-Pyridinecarbonyl-Substituted Renieramycin-Type Derivatives as Potential Cytotoxic Agents against Non-Small-Cell Lung Cancer Cells
por: Sinsook, Suwimon, et al.
Publicado: (2023) -
Chemistry of Renieramycins. Part 19: Semi-Syntheses of 22-O-Amino Ester and Hydroquinone 5-O-Amino Ester Derivatives of Renieramycin M and Their Cytotoxicity against Non-Small-Cell Lung Cancer Cell Lines
por: Chamni, Supakarn, et al.
Publicado: (2020) -
5-O-(N-Boc-l-Alanine)-Renieramycin T Induces Cancer Stem Cell Apoptosis via Targeting Akt Signaling
por: Suksamai, Darinthip, et al.
Publicado: (2022) -
Structure–Activity Relationships and Molecular Docking Analysis of Mcl-1 Targeting Renieramycin T Analogues in Patient-derived Lung Cancer Cells
por: Petsri, Korrakod, et al.
Publicado: (2020)