Cargando…

The Role of AMP-Activated Protein Kinase as a Potential Target of Treatment of Hepatocellular Carcinoma

Background: Hepatocellular carcinoma (HCC) is the fifth most frequent cancer worldwide with a very high recurrence rate and very dismal prognosis. Diagnosis and treatment in HCC remain difficult, and the identification of new therapeutic targets is necessary for a better outcome of HCC treatment. AM...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jiang, Xue, Tan, Hor-Yue, Teng, Shanshan, Chan, Yau-Tuen, Wang, Di, Wang, Ning
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562911/ https://www.ncbi.nlm.nih.gov/pubmed/31083406 http://dx.doi.org/10.3390/cancers11050647

Ejemplares similares

Targeting Hepatic Stellate Cells for the Treatment of Liver Fibrosis by Natural Products: Is It the Dawning of a New Era?
por: Chan, Yau-Tuen, et al.
Publicado: (2020)

PIWIL1 governs the crosstalk of cancer cell metabolism and immunosuppressive microenvironment in hepatocellular carcinoma
por: Wang, Ning, et al.
Publicado: (2021)

The Role of Protein SUMOylation in Human Hepatocellular Carcinoma: A Potential Target of New Drug Discovery and Development
por: Yuan, Hongchao, et al.
Publicado: (2021)

The functional role of long noncoding RNA in resistance to anticancer treatment
por: Qu, Yidi, et al.
Publicado: (2020)

Epigenetic regulation in human cancer: the potential role of epi-drug in cancer therapy
por: Lu, Yuanjun, et al.
Publicado: (2020)

Identification of WT1 as determinant of heptatocellular carcinoma and its inhibition by Chinese herbal medicine Salvia chinensis Benth and its active ingredient protocatechualdehyde
por: Wang, Ning, et al.
Publicado: (2017)

Genipin-activating PPARγ impedes CCR2-mediated macrophage infiltration into postoperative liver to suppress recurrence of hepatocellular carcinoma
por: Wu, Junyu, et al.
Publicado: (2023)

Epigenetic regulation of ferroptosis via ETS1/miR-23a-3p/ACSL4 axis mediates sorafenib resistance in human hepatocellular carcinoma
por: Lu, Yuanjun, et al.
Publicado: (2022)

Lysyl Oxidase‐Like 4 Fosters an Immunosuppressive Microenvironment During Hepatocarcinogenesis
por: Tan, Hor‐Yue, et al.
Publicado: (2021)

Potential Focal Adhesion Kinase Inhibitors in Management of Cancer: Therapeutic Opportunities from Herbal Medicine
por: Chen, Feiyu, et al.
Publicado: (2022)

Ancient Chinese Medicine Herbal Formula Huanglian Jiedu Decoction as a Neoadjuvant Treatment of Chemotherapy by Improving Diarrhea and Tumor Response
por: Chan, Yau-Tuen, et al.
Publicado: (2020)

AMP-Activated Protein Kinase Suppresses the In Vitro and In Vivo Proliferation of Hepatocellular Carcinoma
por: Cheng, Jidong, et al.
Publicado: (2014)

CRISPR-Cas9 library screening approach for anti-cancer drug discovery: overview and perspectives
por: Chan, Yau-Tuen, et al.
Publicado: (2022)

Pancreatic melatonin enhances anti-tumor immunity in pancreatic adenocarcinoma through regulating tumor-associated neutrophils infiltration and NETosis
por: Chan, Yau-tuen, et al.
Publicado: (2023)

Targeting Cyclic AMP Signalling in Hepatocellular Carcinoma
por: Massimi, Mara, et al.
Publicado: (2019)

The Significance of Circulating Tumor Cells in Patients with Hepatocellular Carcinoma: Real-Time Monitoring and Moving Targets for Cancer Therapy
por: Chen, Feiyu, et al.
Publicado: (2020)

New Natural Pigment Fraction Isolated from Saw Palmetto: Potential for Adjuvant Therapy of Hepatocellular Carcinoma
por: Tan, Hor-Yue, et al.
Publicado: (2016)

Deciphering hepatocellular carcinoma through metabolomics: from biomarker discovery to therapy evaluation
por: Guo, Wei, et al.
Publicado: (2018)

Targeting tumour microenvironment by tyrosine kinase inhibitor
por: Tan, Hor-Yue, et al.
Publicado: (2018)

Systematic Review with Meta-Analysis: Effectiveness and Safety of Acupuncture as Adjuvant Therapy for Side Effects Management in Drug Therapy-Receiving Breast Cancer Patients
por: Chan, Yau-Tuen, et al.
Publicado: (2021)

The toxicology and detoxification of Aconitum: traditional and modern views
por: Chan, Yau-Tuen, et al.
Publicado: (2021)

Glutamic-Pyruvic Transaminase 1 Facilitates Alternative Fuels for Hepatocellular Carcinoma Growth—A Small Molecule Inhibitor, Berberine
por: Guo, Wei, et al.
Publicado: (2020)

Thioredoxin-interacting protein-activated intracellular potassium deprivation mediates the anti-tumour effect of a novel histone acetylation inhibitor HL23, a fangchinoline derivative, in human hepatocellular carcinoma
por: Lu, Yuanjun, et al.
Publicado: (2022)

Targeting interleukin-1 receptor-associated kinase 1 for human hepatocellular carcinoma
por: Li, Ning, et al.
Publicado: (2016)

Activation of AMP-activated protein kinase attenuates hepatocellular carcinoma cell adhesion stimulated by adipokine resistin
por: Yang, Chen-Chieh, et al.
Publicado: (2014)

Targeting AMP-Activated Protein Kinase in Aging-Related Cardiovascular Diseases
por: Li, Tian, et al.
Publicado: (2020)

Suppression of lncRNA MALAT1 by betulinic acid inhibits hepatocellular carcinoma progression by targeting IAPs via miR‐22‐3p
por: Chen, Feiyu, et al.
Publicado: (2020)

Integrating Network Pharmacology and Pharmacological Evaluation for Deciphering the Action Mechanism of Herbal Formula Zuojin Pill in Suppressing Hepatocellular Carcinoma
por: Guo, Wei, et al.
Publicado: (2019)

Targeting Cancer Metabolism to Resensitize Chemotherapy: Potential Development of Cancer Chemosensitizers from Traditional Chinese Medicines
por: Guo, Wei, et al.
Publicado: (2020)

IRE1α inhibition by natural compound genipin on tumour associated macrophages reduces growth of hepatocellular carcinoma
por: Tan, Hor-Yue, et al.
Publicado: (2016)

AMP-activated protein kinase pathway: a potential therapeutic target in cardiometabolic disease
por: Wong, Aaron K. F., et al.
Publicado: (2009)

Activation of AMP-activated protein kinase by retinoic acid sensitizes hepatocellular carcinoma cells to apoptosis induced by sorafenib
por: Ishijima, Naoki, et al.
Publicado: (2015)

Expression of Phosphorylated AMP-Activated Protein Kinase Predicts Response to Transarterial Chemoembolization in Postoperative Cases of Hepatocellular Carcinoma
por: Zheng, Long-Yi, et al.
Publicado: (2016)

AMP-activated protein kinase: An emerging target for ginseng
por: Jeong, Kyong Ju, et al.
Publicado: (2013)

Targeting AMP‐activated kinase impacts hepatocellular cancer stem cells induced by long‐term treatment with sorafenib
por: Bort, Alicia, et al.
Publicado: (2019)

Xihuang pills induce apoptosis in hepatocellular carcinoma by suppressing phosphoinositide 3-kinase/protein kinase-B/mechanistic target of rapamycin pathway
por: Teng, Yong-Jie, et al.
Publicado: (2022)

Cancer Stem Cells: The Potential Targets of Chinese Medicines and Their Active Compounds
por: Hong, Ming, et al.
Publicado: (2016)

Interpreting the Pharmacological Mechanisms of Huachansu Capsules on Hepatocellular Carcinoma Through Combining Network Pharmacology and Experimental Evaluation
por: Huang, Jihan, et al.
Publicado: (2020)

LETM1 Knockdown Promotes Autophagy and Apoptosis Through AMP-Activated Protein Kinase Phosphorylation-Mediated Beclin-1/Bcl-2 Complex Dissociation in Hepatocellular Carcinoma
por: Zhou, Baoyong, et al.
Publicado: (2021)

AMP-activated protein kinase: a potential therapeutic target for triple-negative breast cancer
por: Cao, Wei, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_gdfbkai4f1i7jj5vvo21s2fprc