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Protein Hydroxylation by Hypoxia-Inducible Factor (HIF) Hydroxylases: Unique or Ubiquitous?

All metazoans that utilize molecular oxygen (O(2)) for metabolic purposes have the capacity to adapt to hypoxia, the condition that arises when O(2) demand exceeds supply. This is mediated through activation of the hypoxia-inducible factor (HIF) pathway. At physiological oxygen levels (normoxia), HI...

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Detalles Bibliográficos
Autores principales:	Strowitzki, Moritz J., Cummins, Eoin P., Taylor, Cormac T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562979/ https://www.ncbi.nlm.nih.gov/pubmed/31035491 http://dx.doi.org/10.3390/cells8050384

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