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Microbial Genes for a Circular and Sustainable Bio-PET Economy

Plastics have become an important environmental concern due to their durability and resistance to degradation. Out of all plastic materials, polyesters such as polyethylene terephthalate (PET) are amenable to biological degradation due to the action of microbial polyester hydrolases. The hydrolysis...

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Autores principales: Salvador, Manuel, Abdulmutalib, Umar, Gonzalez, Jaime, Kim, Juhyun, Smith, Alex A., Faulon, Jean-Loup, Wei, Ren, Zimmermann, Wolfgang, Jimenez, Jose I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562992/
https://www.ncbi.nlm.nih.gov/pubmed/31100963
http://dx.doi.org/10.3390/genes10050373
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author Salvador, Manuel
Abdulmutalib, Umar
Gonzalez, Jaime
Kim, Juhyun
Smith, Alex A.
Faulon, Jean-Loup
Wei, Ren
Zimmermann, Wolfgang
Jimenez, Jose I.
author_facet Salvador, Manuel
Abdulmutalib, Umar
Gonzalez, Jaime
Kim, Juhyun
Smith, Alex A.
Faulon, Jean-Loup
Wei, Ren
Zimmermann, Wolfgang
Jimenez, Jose I.
author_sort Salvador, Manuel
collection PubMed
description Plastics have become an important environmental concern due to their durability and resistance to degradation. Out of all plastic materials, polyesters such as polyethylene terephthalate (PET) are amenable to biological degradation due to the action of microbial polyester hydrolases. The hydrolysis products obtained from PET can thereby be used for the synthesis of novel PET as well as become a potential carbon source for microorganisms. In addition, microorganisms and biomass can be used for the synthesis of the constituent monomers of PET from renewable sources. The combination of both biodegradation and biosynthesis would enable a completely circular bio-PET economy beyond the conventional recycling processes. Circular strategies like this could contribute to significantly decreasing the environmental impact of our dependence on this polymer. Here we review the efforts made towards turning PET into a viable feedstock for microbial transformations. We highlight current bottlenecks in degradation of the polymer and metabolism of the monomers, and we showcase fully biological or semisynthetic processes leading to the synthesis of PET from sustainable substrates.
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spelling pubmed-65629922019-06-17 Microbial Genes for a Circular and Sustainable Bio-PET Economy Salvador, Manuel Abdulmutalib, Umar Gonzalez, Jaime Kim, Juhyun Smith, Alex A. Faulon, Jean-Loup Wei, Ren Zimmermann, Wolfgang Jimenez, Jose I. Genes (Basel) Review Plastics have become an important environmental concern due to their durability and resistance to degradation. Out of all plastic materials, polyesters such as polyethylene terephthalate (PET) are amenable to biological degradation due to the action of microbial polyester hydrolases. The hydrolysis products obtained from PET can thereby be used for the synthesis of novel PET as well as become a potential carbon source for microorganisms. In addition, microorganisms and biomass can be used for the synthesis of the constituent monomers of PET from renewable sources. The combination of both biodegradation and biosynthesis would enable a completely circular bio-PET economy beyond the conventional recycling processes. Circular strategies like this could contribute to significantly decreasing the environmental impact of our dependence on this polymer. Here we review the efforts made towards turning PET into a viable feedstock for microbial transformations. We highlight current bottlenecks in degradation of the polymer and metabolism of the monomers, and we showcase fully biological or semisynthetic processes leading to the synthesis of PET from sustainable substrates. MDPI 2019-05-16 /pmc/articles/PMC6562992/ /pubmed/31100963 http://dx.doi.org/10.3390/genes10050373 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Salvador, Manuel
Abdulmutalib, Umar
Gonzalez, Jaime
Kim, Juhyun
Smith, Alex A.
Faulon, Jean-Loup
Wei, Ren
Zimmermann, Wolfgang
Jimenez, Jose I.
Microbial Genes for a Circular and Sustainable Bio-PET Economy
title Microbial Genes for a Circular and Sustainable Bio-PET Economy
title_full Microbial Genes for a Circular and Sustainable Bio-PET Economy
title_fullStr Microbial Genes for a Circular and Sustainable Bio-PET Economy
title_full_unstemmed Microbial Genes for a Circular and Sustainable Bio-PET Economy
title_short Microbial Genes for a Circular and Sustainable Bio-PET Economy
title_sort microbial genes for a circular and sustainable bio-pet economy
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562992/
https://www.ncbi.nlm.nih.gov/pubmed/31100963
http://dx.doi.org/10.3390/genes10050373
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