Cargando…

Phytochemical Combination PB125 Activates the Nrf2 Pathway and Induces Cellular Protection against Oxidative Injury

Bioactive phytochemicals in Rosmarinus officinalis, Withania somnifera, and Sophora japonica have a long history of human use to promote health. In this study we examined the cellular effects of a combination of extracts from these plant sources based on specified levels of their carnosol/carnosic a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hybertson, Brooks M., Gao, Bifeng, Bose, Swapan, McCord, Joe M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563026/ https://www.ncbi.nlm.nih.gov/pubmed/31058853 http://dx.doi.org/10.3390/antiox8050119

Ejemplares similares

Nrf2 Activator PB125® as a Potential Therapeutic Agent Against COVID-19
por: McCord, Joe M., et al.
Publicado: (2020)

Effects of the Phytochemical Combination PB123 on Nrf2 Activation, Gene Expression, and the Cholesterol Pathway in HepG2 Cells
por: Hybertson, Brooks M., et al.
Publicado: (2022)

Nrf2 Activator PB125(®) as a Potential Therapeutic Agent against COVID-19
por: McCord, Joe M., et al.
Publicado: (2020)

Nrf2 activator PB125® as a carnosic acid-based therapeutic agent against respiratory viral diseases, including COVID-19()
por: McCord, Joe M., et al.
Publicado: (2021)

The Complex Genetic and Epigenetic Regulation of the Nrf2 Pathways: A Review
por: McCord, Joe M., et al.
Publicado: (2023)

Phytochemical Activation of Nrf2 Protects Human Coronary Artery Endothelial Cells against an Oxidative Challenge
por: Donovan, Elise L., et al.
Publicado: (2012)

The clinical potential of influencing Nrf2 signaling in degenerative and immunological disorders
por: Gao, Bifeng, et al.
Publicado: (2014)

Protandim Protects Oligodendrocytes against an Oxidative Insult
por: Lim, Jamie L., et al.
Publicado: (2016)

Neuroprotection Against Oxidative Stress: Phytochemicals Targeting TrkB Signaling and the Nrf2-ARE Antioxidant System
por: Hannan, Md. Abdul, et al.
Publicado: (2020)

Phytochemical activators of Nrf2: a review of therapeutic strategies in diabetes: Phytochemical activators of Nrf2
por: Qin, Si, et al.
Publicado: (2022)

Role of NRF2 in protection of the gastrointestinal tract against oxidative stress
por: Yanaka, Akinori
Publicado: (2018)

Eugenol protects cells against oxidative stress via Nrf2
por: Ma, Leina, et al.
Publicado: (2021)

Protective Effects of a Polyphenolic Phytochemical Quercetin against Oxidative Dysfunctions in Rats
por: Foudah, Ahmed I., et al.
Publicado: (2023)

The role of intracellular zinc release in aging, oxidative stress, and Alzheimer’s disease
por: McCord, Meghan C., et al.
Publicado: (2014)

Nrf2 Activators as Dietary Phytochemicals Against Oxidative Stress, Inflammation, and Mitochondrial Dysfunction in Autism Spectrum Disorders: A Systematic Review
por: Yang, Jiaxin, et al.
Publicado: (2020)

Epigenetic Regulation of NRF2/KEAP1 by Phytochemicals
por: Bhattacharjee, Shamee, et al.
Publicado: (2020)

Preconditioning the immature lung with enhanced Nrf2 activity protects against oxidant-induced hypoalveolarization in mice
por: Tamatam, Chandra M., et al.
Publicado: (2020)

Targeting Nrf2-Mediated Oxidative Stress Response in Traumatic Brain Injury: Therapeutic Perspectives of Phytochemicals
por: Wu, An-Guo, et al.
Publicado: (2022)

Aspalathin Protects the Heart against Hyperglycemia-Induced Oxidative Damage by Up-Regulating Nrf2 Expression
por: Dludla, Phiwayinkosi V., et al.
Publicado: (2017)

Genetic Activation of Nrf2 Protects against Fasting-Induced Oxidative Stress in Livers of Mice
por: Zhang, Yu-Kun Jennifer, et al.
Publicado: (2013)

Trehalose protects against oxidative stress by regulating the Keap1–Nrf2 and autophagy pathways
por: Mizunoe, Yuhei, et al.
Publicado: (2017)

Apigenin Protects Mouse Retina against Oxidative Damage by Regulating the Nrf2 Pathway and Autophagy
por: Zhang, Yuanzhong, et al.
Publicado: (2020)

Grub polypeptide extracts protect against oxidative stress through the NRF2-ARE signaling pathway
por: Chen, Jingyang, et al.
Publicado: (2021)

Dietary Phytochemicals Targeting Nrf2 to Enhance the Radiosensitivity of Cancer
por: Wang, Pinghan, et al.
Publicado: (2022)

Role of Phytochemicals in Skin Photoprotection via Regulation of Nrf2
por: Chaiprasongsuk, Anyamanee, et al.
Publicado: (2022)

Bioactivity Potential of Prunus spinosa L. Flower Extracts: Phytochemical Profiling, Cellular Safety, Pro-inflammatory Enzymes Inhibition and Protective Effects Against Oxidative Stress In Vitro
por: Marchelak, Anna, et al.
Publicado: (2017)

MMPI-2-RF : una guía para la interpretación /
por: McCord, David M.
Publicado: (2019)

Sulforaphane as a Potential Protective Phytochemical against Neurodegenerative Diseases
por: Tarozzi, Andrea, et al.
Publicado: (2013)

Role of Oxidative Stress and Nrf2/KEAP1 Signaling in Colorectal Cancer: Mechanisms and Therapeutic Perspectives with Phytochemicals
por: Lee, Da-Young, et al.
Publicado: (2021)

Phytochemical-rich herbal formula ATG-125 protects against sucrose-induced gastrocnemius muscle atrophy by rescuing Akt signaling and improving mitochondrial dysfunction in young adult mice
por: Yeh, Ching-Chuan, et al.
Publicado: (2022)

Vicarious Hæmoptysis
por: McCord, J. S.
Publicado: (1876)

Polydatin Protects Bone Marrow Stem Cells against Oxidative Injury: Involvement of Nrf 2/ARE Pathways
por: Chen, Meihui, et al.
Publicado: (2016)

Bixin protects mice against ventilation-induced lung injury in an NRF2-dependent manner
por: Tao, Shasha, et al.
Publicado: (2016)

Roles of Nrf2 in Protecting the Kidney from Oxidative Damage
por: Nezu, Masahiro, et al.
Publicado: (2020)

Nrf2, the Major Regulator of the Cellular Oxidative Stress Response, is Partially Disordered
por: Karunatilleke, Nadun C., et al.
Publicado: (2021)

The Role of Nrf2 Signaling in PPARβ/δ-Mediated Vascular Protection against Hyperglycemia-Induced Oxidative Stress
por: Jimenez, Rosario, et al.
Publicado: (2018)

Icariin and Its Metabolites as Potential Protective Phytochemicals Against Alzheimer’s Disease
por: Angeloni, Cristina, et al.
Publicado: (2019)

Activation of Nrf2 Protects against Triptolide-Induced Hepatotoxicity
por: Li, Jia, et al.
Publicado: (2014)

Nrf2 Is a Protective Factor against Oxidative Stresses Induced by Diesel Exhaust Particle in Allergic Asthma
por: Li, Ying-Ji, et al.
Publicado: (2013)

Protection against oxidative stress mediated by the Nrf2/Keap1 axis is impaired in Primary Biliary Cholangitis
por: Wasik, Urszula, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_1efidj03eak3enk87j9kil6ahm