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Perturbing Enhancer Activity in Cancer Therapy

Tight regulation of gene transcription is essential for normal development, tissue homeostasis, and disease-free survival. Enhancers are distal regulatory elements in the genome that provide specificity to gene expression programs and are frequently misregulated in cancer. Recent studies examined va...

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Detalles Bibliográficos
Autores principales: Hamdan, Feda H., Johnsen, Steven A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563029/
https://www.ncbi.nlm.nih.gov/pubmed/31067678
http://dx.doi.org/10.3390/cancers11050634