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Preserving Genome Integrity during the Early Embryonic DNA Replication Cycles

During the very early stages of embryonic development chromosome replication occurs under rather challenging conditions, including a very short cell cycle, absence of transcription, a relaxed DNA damage response and, in certain animal species, a highly contracted S-phase. This raises the puzzling qu...

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Detalles Bibliográficos
Autores principales: Kermi, Chames, Aze, Antoine, Maiorano, Domenico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563053/
https://www.ncbi.nlm.nih.gov/pubmed/31137726
http://dx.doi.org/10.3390/genes10050398